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Keynote Lectures

Non-Invasive Disease Diagnosis Using Wearable Sensing Technologies
Hossam Haick, Israel Institute of Technology, Israel

Project Based Learning and Biomedical Devices: The UBORA Approach Towards an International Community of Developers Focused on Open-Source Medical Devices
Andres Diaz Lantada, Universidad Politecnica de Madrid, Spain

Ehealth in Portugal and EU
Henrique Martins, Universidade da Beira Interior, Portugal

 

Non-Invasive Disease Diagnosis Using Wearable Sensing Technologies

Hossam Haick
Israel Institute of Technology
Israel
 

Brief Bio

Hossam Haick, an expert in the field of nanotechnology and non-invasive disease diagnosis, is a full professor and the F.M.W. Academic Chair in the Department of Chemical Engineering and the Russell Berrie Nanotechnology Institute at the Technion – Israel Institute of Technology. Prof. Haick received his B.Sc. and Ph.D. (direct track) in Chemical Engineering from the Ben-Gurion University (1998) and the Technion (2002) respectively.  After a two-year period at the Weizmann Institute of Science (2002-2004), he moved to the California Institute of Technology – Caltech (2004-2006) for postdoctoral research, and then to the Technion as an assistant professor in 2006.

At the Technion, Prof. Haick has made a significant mark through his development of artificially intelligent nanoarray technology to detect diseases non-invasively.  This work has earned him prestigious grants: the Marie Curie Excellence Grant, the ERC and the Bill & Melinda Gates Foundation Award. Among the many consortia Prof. Haick has coordinated are the FP-7 consortium (LCAOS; 2011-2015), a EuroNanoMed II consortium (VOLGACORE; 2014-2017), and the Horizon2020 ICT consortium (SNIFFPHONE; 2015-2019).


Abstract
The lecture will present innovative technologies developed by our research group at the Technion. These technologies are non-invasive disease diagnosis tools that do not require needles or use of dangerous materials. The lecture will present, amongst other things, an electronic system that simulates the canine olfactory system and that detect diseases from exhaled breath. This system is known as “Nano-Artificial Nose”. Clinical trials worldwide have shown that this system can detect 17 different diseases, including various cancers, neurological disorders and infectious diseases - all though a simple breath test. The lecture will also present the development and miniaturization of intelligent wearable technology that integrates functions similar to those in the human skin. This technology, known as the "Electronic Skin", has been found effective in monitoring a wide range of health indicators and help in disease diagnosis in both the developing and developed world. The link of these technologies to a unique information cloud, where the analysis of data takes place and results are sent back to the user or their personal physician, will be presented and discussed as well.



 

 

Project Based Learning and Biomedical Devices: The UBORA Approach Towards an International Community of Developers Focused on Open-Source Medical Devices

Andres Diaz Lantada
Universidad Politecnica de Madrid
Spain
 

Brief Bio
Andrés Díaz Lantada is Associate Professor at the Department of Mechanical Engineering at the Industrial Engineering School from Universidad Politécnica de Madrid (ETSII-UPM). He finished his 6-year Industrial Engineering Degree in 2005 and his PhD Theses in 2009, which received Extraordinary PhD Award by Universidad Politécnica de Madrid and 2nd PhD Award by the Council of Industrial Engineers of Madrid. His research interests are linked to the development of mechanical systems and biomedical devices with improved capabilities, thanks to the incorporation of smart materials, special geometries and complex functional surfaces and structures, mainly attainable by means of additive manufacturing processes. He is currently UPM Contact Researcher at the “European Virtual Institute of Knowledge-Based Multifunctional Materials”, UPM Leader at the “UBORA: Euro-African Open Biomedical Engineering e-Platform for Innovation through Education” project, funded by the EU H2020 programme within the “Support to policy and international cooperation” call, and Director of the UPM Product Development Laboratory. He has also led the research activities of UPM within the “TOMAX: Tool-less manufacturing of complex structures” project, funded by the EU H2020 programme within the “Factories of the future” call. He has directed 2PhD Theses and more than 100 MSc and BSc final degree theses. He has received the “UPM Teaching Innovation Award” in 2014, the “UPM Young Researcher Award” in 2014, and the “Medal to Researchers under 40” by the “Spanish Royal Academy of Engineering” in 2015. Since January 2016 he has the honour of being Member of the Editorial Advisory Board of the International Journal of Engineering Education. His current research dedication is to the field of open-source medical devices for the democratization of medical technology, in connection with the UBORA community and with the UBORA e-infrastructure, and to the development of innovative teaching-learning methodologies in the biomedical engineering field.


Abstract
The engineering design of successful medical devices relies on several key factors, including: orientation to patients’ needs, collaboration with medical professionals through the whole development process and the compromise of multi-disciplinary teams formed by well-trained professionals, especially biomedical engineers, capable of understanding the connections between science, technology and health and guiding such developments. Preparing engineers in general and biomedical engineers in particular to work in the medical industry, in connection with biodevice development, is a challenging process, through which the trainee should acquire a broad overview of the medical field and biomedical industry, a well-balanced combination of general and specific knowledge, according to the chosen specialization, several technical abilities linked to modern engineering tools and a wide set of professional skills. Among the existing teaching-learning methodologies that can be employed for providing such holistic training, project-based learning, especially in connection with the CDIO “conceive-design-implement-operate” approach applied to the biomedical field, is presented here and illustrated by means of successful experiences. Besides, new approaches to the development of innovative medical devices, including open-source and collaborative engineering design strategies, which are bound to impact the medical industry in a relevant way in the very near future and support the democratization of medical technology, by giving voice to medical professionals, patients and citizens, need to be also considered when preparing the “biomedical engineers of the future”. Trends in the field of collaboratively developed open-source medical devices (OSMD) are presented and main current R&D challenges analyzed. Finally, the “UBORA” project is highlighted as a paradigmatic example. This Euro-African initiative is focused on the promotion of OSMD by means of innovation through education, by the creation of a “Wikipedia” of medical devices, the “UBORA e-infrastructure”, which also guides designers in the engineering design process and supports online collaboration through the process, and by the constitution of an international community of developers devoted to OSMD. Results from project-based learning within the first International UBORA Design Competitions and the first International UBORA Design Schools (Nairobi 2017 & Pisa 2018) are presented. The “UBORA e-infrastructure” and the more than 50 open-source biodevices developed in collaboration by around 200 users, and shared through such online platform, are also analyzed.



 

 

Ehealth in Portugal and EU

Henrique Martins
Universidade da Beira Interior
Portugal
 

Brief Bio
Prof. Martins is an Internal Medicine Specialist. He obtained his PhD degree from the Judge Business School, University of Cambridge with a thesis on “The use of Mobile ICT in clinical Settings”. He holds a Master in Management from the University of Cambridge on “How to teach Management and Leadership to Medical Studentes” and a Masters in HIV/AIDS from the University of Barcelona. He has several publications in the area of Mobile computing in healthcare and many conference presentations/keynotes in the area of eHealth.
He is the President of the Board of SPMS (www.spms.min-saude.pt) the Shared Services and eHealth/IT authority of the Ministry of Health, since April 2013 until present date, after having served for 2 years as Adjunct for Health IT to the Health Secretary of State of Portugal. He was responsible for setting up the Health Information Sharing Platform for Electronic Health Records in Portugal, Nationwide ePrescription/eDispensation, national vaccination records, and many other national ehealth projects. He is the representative for Portugal at the eHealth Network (https://ec.europa.eu/health/ehealth/policy/network_en), the EU body responsible for eHealth Policy in the Union, since its creation in 2012 and the elected Member State chair since 2018. He has been participant in several EU funded interoperability projects, like epSOS and others and the coordinator of EXPAND thematic Network, and is presently the coordinator of the joint action from EC to work on fostering eHealth in Europe with more than 27 Members States (eHealth Action – http://jointaction3.spms.min-saude.pt/). In the past he has worked as CMIO – Chief Medical Information Officer at Hospital Fernando Fonseca for 5 years. He started and coordinated for 3 years the Center for Investigation and Creativity in Informatics (www.ci2.pt), where he supervised projects in robotics, mobile computing and database exploration and intelligent systems. He has been Health Executive education coordinator for more than 10 years at FT-Ranked Catholic Lisbon Business School, and presently teaches health management, leadership and medical informatics in Portugal and abroad both at top management schools as well as medical and other health professionals’ schools.


Abstract
European health care sector is facing challenges resulting from economic crisis, demography, ageing population and increase of chronic diseases. However, digital society and digitalisation are creating opportunities in society across sectors and in healthcare, by transforming the way healthcare services are provided, information access, secondary use of data, communication between citizens and healthcare providers, citizens access to own personal health data and relation with own health. Insuring the conditions that guarantee the progress of change, in line with European guidelines, and, in Portugal with national strategy, National Strategy for the Health Information Ecosystem (ENESIS 2020), is essential for the success and improvement, in an exponential way, of public services provided to citizens. The Shared Services of Ministry in Health, EPE as the entity responsible for Information Systems in Health, has been proactively, leveraging the shift to digital transformation in the health system, based on the objective of improving the information quality and health care management, as well as increasing efficiency and technologically upgrade existing systems. However, robust infrastructures, fast networks and appropriate hardware are vital throughout this process. The portfolio of products, projects and services developed by SPMS, are based on the strategy of simplification and dematerialization, to facilitate and improve citizens’ lives and professionals’ performance, converging to the current Health Programme. Electronic Health Record answers to this priority in three ways: providing standardized solutions to health professionals use in healthcare setting (SONHO and SClínico), promoting healthcare continuity and clinical integration with primary care and continuity of care records, as well as for secondary use of data; allowing the registration and sharing of clinical information between citizens, health professionals and health care providers, including the private sector, complying with requirements of GDPR progressively and allowing for cross-border sharing of patient summaries and ePrescription and Dispensation as off 2018.



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